Nicotine pouches are fibrous pouches with fillers, sweeteners, flavorings and nicotine. Nicotine pouches offer an alternative to other oral tobacco products and give a smoke-free alternative to vapes and combustible tobacco products. These pouches are tobacco leaf-free, smoke-free, and come in many flavor and strength options. As for how nicotine pouches work, they work orally: when the pouch comes in contact with the mucous lining of your mouth – and this is how the nicotine enters your system.